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T-knife, Catalent Sign Tech Transfer and Mfg. Pact for Cell Therapy

Catalent to provide technology transfer and cGMP clinical manufacture of T-knife’s T1367 T-cell receptor program at its site in Gosselies, Belgium.

By: Contract Pharma

Contract Pharma Staff

T-knife GmbH, a next-gen adoptive T-cell company, and Catalent, have signed an agreement to provide technology transfer and CGMP clinical manufacturing of T-knife’s T1367 T-cell receptor (TCR) program. T1367 is an autologous T-cell receptor-based cell therapy derived from T-knife’s proprietary humanized T-cell receptor (HuTCR) mouse platform and specifically targets MAGE-A1 positive tumors in cancer patients. The therapy is expected to be manufactured for clinical trials in both the EU and U...

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